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trial, the composite endpoint Therapeutic Response was a key secondary endpoint. Patients should be informed that deterioration of liver disease may occur in some cases if treatment is discontinued, and that they should discuss any change in regimen with their physician. Peripheral Neuropathy Peripheral neuropathy has been reported with Tyzeka alone or in combination with pegylated interferon alfa-2a and other interferons. Tyzeka therapy should be interrupted if peripheral neuropathy is suspected, and discontinued if peripheral neuropathy is confirmed see Adverse Reactions (6.1). Racial/Ethnic Minorities The safety and efficacy of Tyzeka have not been evaluated in Black/African American or Hispanic patients. .
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HBeAg-positive Subjects: traxxas monster truck coupon (n 458 Tyzeka; n 463 lamivudine) The mean age of subjects was 32 years, 74 were male, 82 were Asian, 12 were Caucasian, and 6 had previously received alfa-interferon therapy. In addition, Tyzeka does not alter the pharmacokinetics of lamivudine, adefovir dipivoxil, cyclosporine, or tenofovir disoproxil fumarate. Particular caution should be exercised when administering HBV nucleoside analogue reverse transcriptase inhibitors to patients with known risk factors for liver disease; however, cases have also been reported in patients with no known risk factors. Lactic acidosis is a serious medical emergency that can lead to death. Tyzeka will not cure HBV.
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